Concurrent Development of Systemic Lupus Erythematosus and Neuromyelitis Optica
Hyun-Ju Park, MD, Seok-Beom Kwon, MD, PhD, San Jung, MD and Sung-Hee Hwang, MD, PhD
Department of Neurology, Hallym University College of Medicine, Seoul, Korea
ABSTRACT
Background: Neuromyelitis optica (NMO) is one of rare and serious neurological manifestations of systemic lupus erythematosus (SLE) and is diagnosed by optic neuritis, myelitis, 3 or more contiguous spinal cord segments involvement and seropositivity for anti-NMO IgG. We report a case of patient with NMO fully satisfied with Wingerchuck’s criteria as the first manifestation of SLE. Case Report: A 30-yearold woman with two times of optic neuritis was admitted due to reduced vision, lower leg tingling sensation and weakness. She was diagnosed as NMO with right optic neuritis, longitudinal transverse myelitis, and positive for anti-NMO IgG. The diagnosis of SLE was based on positivity for antinuclear antibody, anti-double stranded DNA, leukopenia, proteinuria. She received intravenous high dose methylprednisolone. Sensory impairment was improved. Conclusions: To the best of our knowledge, this patient is the first SLE case with NMO satisfied all of Wingerchuck’s criteria.
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