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J Neurocrit Care 2009;2(1): 15-17.
Five Cases of Cerebral Infarction in Patients with Anemia and Severe Atherosclerotic Narrowing in Intracranial Artery
Eui-Seong Lim, MD1 and Byoung-Soo Shin, MD, PhD2,3
1Department of Neurology, Cham Hospital, Seoul, Korea 2Departments of Neurology, Chonbuk National University Medical School, Jeonju, Korea 3Research Institute of Clinical Medicine, Chonbuk National University Hospital, Jeo
ABSTRACT
Background: Anemic hypoxia is characterized by reduced hemoglobin content with normal arterial oxygen tension and saturation. Paients with severe atherosclerotic narrowing in brain lack the reserve capacity to preserve tissue oxygenation in reduced hemoglobin level. We evaluate the effect of anemia in severe atherosclerotic narrowing in cerebral vasculature.
Case Report: We present five patients with severe atherosclerotic lesion who developed transient or permanent neurological deficits occurred during a severe anemia and recovered or improved after transfusion.
Conclusions: Iron deficiency should be considered in the differential diagnosis of vascular events and treated as a preventive measure in reducing the risk of stroke in the severe atherosclerotic narrowing in cerebral vasculature.
Key Words: Anemic hypoxia·Atherosclerosis·Brain infarction
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