Department of Neurology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea
ABSTRACT
The treatment of epilepsy extends far beyond seizure control. Many comorbidities have a significant impact on the medical management and quality of life of patients with epilepsy. Adequate recognition and treatment of psychiatric conditions in epilepsy is essential for patients management because of their considerable burden in morbidity and quality of life. In this review, the effects of medical comorbid conditions are reviewed, including the effects of antiepileptic medications on brain tumor, thyroid disease, diabetes, psychiatric disorders, migraine, and neuropathic pain on pharmacological therapy of epilepsy.