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J Neurocrit Care 2008;1(2): 171-173.
부갑상샘기능저하증과 간질이 동반된 양측 줄무늬창백치아 석회증
서경임, 김선정·김도현·최영철·김원주
연세대학교 의과대학 강남세브란스병원 신경과학교실
Bilateral Striatopallidodentate Calcinosis in a Patient with Hypoparathyroidism and Epilepsy
Gyoungim Suh, MD Seon Jeong Kim, MD, Do Hyun Kim, MD, Young-Chul Choi, MD and Won-Joo Kim, MD
Department of Neurology, College of Medicine, Yonsei University, Gangnam Severance Hospital, Seoul, Korea
Background: Basal ganglia calcification is one of the features of chronic hypocalcemia. However, extensive intracranial symmetrical calcifications outside the basal ganglia have been reported relatively rare in patients with hypoparathyroidism.
Case Report: A 36 years old woman with a history of hypoparathyroidism and epilepsy for 20 years presented with a generalized tonic-clonic seizures. A non-enhanced computed tomography scan showed bilateral and symmetrical calcifications in basal ganglia, cerebellum, thalamus and subcortical white matter. Laboratory studies included a ionized calcium 0.71 mmol/L, phosphate 6.4 mg/dL, and parathyroid hormone less than 3.0 pg/mL (10-65 pg/mL). Her medication was only calcium gluconate. We added an antiepileptic drug for epilepsy.
Conclusions: We reported a case with bilateral striatopallidodentate calcinosis with hypoparathyroidism and epilepsy.
Key Words: Calcification·Hypoparathyroidism·Epilepsy
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