Department of Neurology, Hangang Sacred Heart Hospital, Hallym University, Seoul, Korea
ABSTRACT
Alchohol withdrawal delirium is the most serious manifestation of alcohol withdrawal and recognizes as a potentially fatal. It is known that both gamma-aminobutyric acid type-A (GABAA) and N-methyl-D-aspartate (NMDA) receptors are involved in alcohol withdrawal symptoms. Clinical feature of alcohol withdrawal symptome can appear within hours of last drink, but delirium typically dose not develop until 2 to 3 days after cessation od drinking. Control of agitation should be achieved using rapid-acting sedative-hypnotic agent.
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