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J Neurocrit Care 2013;6(2): 115-118.
광범위한 대뇌피질 병변과 발작에도 불구하고 좋은 예후를 보인 베르니케뇌병증 1예
류 성 근·이 세 진
영남대학교 의과대학 신경과학교실
A Case of Clinically Reversible Wernicke Encephalopathy in Spite of Extensive Cortical Involvement and Seizure
Sung Geun Ryu, MD and Se-Jin Lee, MD, PhD
Department of Neurology, Yeungnam University College of Medicine, Daegu, Korea
Background: There have been few reports of reversible Wernicke encephalopathy with extensive cortical involvement.
Case Report: A 57-year-old female, a chronic alcohol-abuser, presented with acute confusional state, ataxia, ophthalmoplegia and seizure. Brain magnetic resonance imaging showed brain lesions at the bilateral periaqueductal gray matter, mammillary bodies and median thalami, which were indicative of Wernicke encephalopathy. In addition, extensive symmetric frontal cortical lesions were observed. After administration of intravenous thiamine, the patient recovered almost completely.
Conclusions: A patient with Wernicke encephalopathy complicated by extensive cerebral cortical lesion may recover after appropriate treatment.
Key Words: Wernicke encephalopathy · Cerebral cortex · Prognosis
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A Case of Atypical Wernicke’s Encephalopathy Showing Symmetric Cortical Lesions on MRI  2013 December;6(1)
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